MPRIME Transition, New Electronic Medication Prior Authorization Submission Process and Upcoming Medicaid Renewal Changes

Posted on 2026-08-26 | Updated on 2026-09-08 18:59:11

This communication includes important updates for CareFirst Community Health Plan Maryland providers, including Maryland Medicaid’s transition to MPRIME, the upcoming change for how to enter medication prior authorizations, and important Medicaid coverage renewal information for 2027.

MPRIME Transition Update

As shared in our BlueLink Newsletters, Maryland Medicaid is transitioning from the Electronic Provider Revalidation and Enrollment Portal (ePREP) to the Maryland Provider Registration and Information Management Enterprise (MPRIME) portal. The Maryland Department of Health (MDH) is targeting October 13, 2026, for MPRIME go-live.

MPRIME will become the new portal for Maryland Medicaid provider enrollment, revalidation and enrollment account updates. Providers should review MDH’s transition guidance and take steps now to prepare for the upcoming change.

Key Dates

  • July 1, 2026: ePREP applications were no longer accepted for high- and moderate-risk provider types.
  • August 1, 2026: ePREP applications were no longer accepted for limited-risk provider types.
  • August–September 2026: MDH will offer MPRIME system training for providers.
  • October 13, 2026: Target go-live date for MPRIME.

Provider Training Available

MDH is offering MPRIME system training to help providers and office staff prepare for the transition. Providers are encouraged to register for training and share this information with staff who support enrollment, credentialing, billing or administrative updates.

What Providers Should Do Now

  • Register for MDH’s MPRIME training and ensure appropriate administrative, billing and credentialing staff attend.
  • Monitor MDH communications for additional implementation guidance, FAQs and training updates.
  • Plan for the transition, as providers will need to wait until MPRIME is available to make enrollment updates once the application hold is in effect.

Questions

For more information or if you have questions about this transition, visit MDH’s MPRIME provider enrollment page at https://health.maryland.gov/mmcp/provider/Pages/mprime.aspx or email MDH at mdh.mprimegolive@maryland.gov.

New Electronic Medication Prior Authorization Submission Process Effective October 1, 2026

We are pleased to announce that, beginning October 1, 2026, you can submit Medication Prior Authorization requests electronically for your CareFirst CHPMD members using the CareFirst Provider Portal (CareFirst Direct).

For complete step-by-step instructions, access the How to Enter Medication Prior Authorizations course.

Register for a Live Webinar

In addition to the on-demand training available, we are offering several live webinars to walk through the process of entering medication prior authorization requests electronically.

To register, select the date and time below through the provided link:

Additional Information

Please refer to the provider news alert email sent on July 14, 2026, for more details.

Upcoming Maryland Medicaid Changes

Beginning January 1, 2027, some Maryland Medicaid members may need to meet new federal work and renewal requirements to maintain coverage. Help members stay informed by directing them to MarylandHealthConnection.gov/Checkin and reviewing the Maryland Department of Health provider toolkit for resources you can use in your practice.